With "feasibility" CPLEX puts more effort on finding feasible solutions early in the solution process. This is done for example by running heuristics more frequently. The "feasiblity" emphasis is useful if it is hard for CPLEX to find feasible solutions to your problem.
With "optimality" CPLEX puts more effort on proving the optimality on the feasible solution it finds. This is useful if finding feasible solutions is relatively simple but proving their optimality looks hard.
In short terms, "feasibility" focuses on improving the primal bound while "optimality" focuses on improving the dual bound.
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