I would start by looking at this issue APAR IJ25315 to apply the workaround described in this issue.
If you continue to have problems, then you can look at an update your the settings for smtp_host_lookup. This issue might be due to a config and by changing smtp_host_lookup=dns, native to smtp_host_lookup=native
it might fix the issue. If DNS server cannot find A/AAAA record, it
should return "NXDOMAIN", while in this case it returned "SERVFAIL".
The reason for this is that DNS was expecting domain name as part of the
hostname, so "mailserver" resolution would fail, but
"mailserver.YOURDOMAIN.com" succeeds.
If you aren't sure how to make this change or confirm the issue, open a case with QRadar Support and they review the APAR workaround is applied and that rule response emails trigger correctly.
Edit: This issue was indeed introduced in 7.4.x due to a postfix update in RHEL. I believe there is also info here: https://access.redhat.com/solutions/4647781
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