A little more details on @BEN FORSYTH answer:
Node API answers are limited in size by the value of the parameter: max_request_file_create_size_kb in aspera.conf.
One can get the active value of that parameter with command:
$ asuserdata -a | grep max_request_file_create_size_kb
max_request_file_create_size_kb: "20000"
Or alternatively:
$ asconfigurator -x "get_server_data"|grep max_request_file_create_size_kb
"server","max_request_file_create_size_kb","20000","4096"
The first value here is the actual value, and the second value is the default value.
If the value is >= 16 MebiBytes (i.e. 2**24), then the value is maxed out to that value.
So, it is possible to increase that value to 16MB with commands:
asconfigurator -x "set_server_data;max_request_file_create_size_kb,20000"
systemctl restart asperanoded
This value also impacts the max size of previews used in AoC.