There is no setting for JDBC connection. Connection pool is shared by concurrent threads. So I don't know if ITX can guarantee the same connection.
However there is a map setting for each output card. By default it's "Map". The other option is "Card".
With "Map", a failed operation will result in a rollback with all the output cards in the map.
Here is the link regarding the scope option.
https://www.ibm.com/docs/en/ste/11.0.2?topic=settings-scope