IS still supports Soap 1.1. ServiceNet 6.5 supports Soap 1.2. Most servers that will accept Soap 1.2 messages will also accept Soap 1.1 messages.
Since the message itself is just an XML document, it is certainly possible to generate or consume Soap 1.2 messages from within Integration Server, although you might want to create a custom soap processor to make this easier. A custom soap processor is just a flow or java service that pre-processes the soap message before invoking some service.
Mark
#API-Management#soa#webMethods