Hi Venkatesh,
can you provide the corresponding entries in the server.log from the IS too?
Additionally it will be good a idea to verify the settings in designer preferences if it is able to connect to the IS (logical server) as well as to the corresponding process audit database.
Please check also the following settings in the IS:
Settings → JDBC-Pools → Process Engine & Process Audit
Settings → Remote Server
Packages → Management → WmDesigner (Logical Server will be associated to the Remote Server here).
Additionally it will be helpful to have the exact Fix-Levels for IS, ProcessEnginge/ProcessRuntime as well as for Designer.
HTH,
Holger
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