If you will exchange messages containing EDI payloads, ensure you have installed the EDI Module (WmEDI) and the EDI Module Trading Networks (WmEDIforTN). (Alternatively, to exchange EDIINT messages with an EDI payload without installing these EDI Module, you can choose to not submit the EDI payload to Trading Networks. From the EDIINT Configuration page, uncheck Submit Payload to TN.)
EDIINT can also be implemented using IS4.6 version.
HTH.
#webMethods#Integration-Server-and-ESB#B2B-Integration