Hi Brent,
Unfortunately I don't find the setting you are mentioning in Edge. I have tried the option from Settings -> Site permissions -> PDF documents: Always open PDF files externally.
With this setting enabled, when I try to open PDFs in ICN I am getting in the viewer the message: "This content is blocked. Contact the site owner to fix the issue."
So, I am not sure what is going wrong here.
In the console of the browser I also get a message in red: "Refused to frame '' because it violates the following Content Security Policy directive: "default-src 'self' blob: https:". Note that 'frame-src' was not explicitly set, so 'default-src' is used as a fallback."
Note: this is happening in our dev environment, where ICN is indeed unsecured on http.
I have tested this setting for SharePoint (opened in Edge), and when I click a PDF, it appears in a toolbar at the bottom of the page, with the options to Open or Save.
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