I ran into null pointer exceptions on the pub.client:soapHTTP call last year when making HTTPS calls to Dotnet (.Net) service providers. The solution was to upgrade to a newer IS 6.5 service pack (SP2 or SP3) and then populate the new loadAs parameter with the value of “byteArrayStream”.
These threads appear related.
I’m not sure that this would help in your case.
Mark
#API-Management#webMethods#soa