After running dnf update we are now seeing this error:

[root@aixsbx1][/] dnf list
exec(): 0509-036 Cannot load program /opt/freeware/bin/python3 because of the following errors:
        0509-130 Symbol resolution failed for /opt/freeware/lib64/libpython3.7m.so because:
        0509-136   Symbol _GLOBAL__AIXI_libintl_so (number 4) is not exported from
                   dependent module /usr/opt/rpm/lib/libintl.a[libintl.so.8].
        0509-136   Symbol _GLOBAL__AIXD_libintl_so (number 5) is not exported from
                   dependent module /usr/opt/rpm/lib/libintl.a[libintl.so.8].
        0509-192 Examine .loader section symbols with the
                 'dump -Tv' command.

if we unset the LIBPATH the error msg changes 
LIBPATH=/hei/tibco/heitest/tibrv/lib:/usr/lib:/usr/emc/esnapi/2_1_28/aix_lib


[root@aixsbx1][/] dnf list
Traceback (most recent call last):
  File "/usr/bin/dnf", line 58, in <module>
    from dnf.cli import main
  File "/opt/freeware/lib/python3.7/site-packages/dnf/__init__.py", line 30, in <module>
    import dnf.base
  File "/opt/freeware/lib/python3.7/site-packages/dnf/base.py", line 29, in <module>
    import libdnf.transaction
  File "/opt/freeware/lib64/python3.7/site-packages/libdnf/__init__.py", line 3, in <module>
    from . import common_types
  File "/opt/freeware/lib64/python3.7/site-packages/libdnf/common_types.py", line 13, in <module>
    from . import _common_types
ImportError:    0509-022 Cannot load module /opt/freeware/lib64/librepo.a(librepo.so.0).
        0509-150   Dependent module /opt/freeware/lib/libcrypto.a(libcrypto.so.1.0.2) could not be loaded.
        0509-152   Member libcrypto.so.1.0.2 is not found in archive
        0509-022 Cannot load module /opt/freeware/lib64/python3.7/site-packages/libdnf/_common_types.so.
        0509-150   Dependent module /opt/freeware/lib64/librepo.a(librepo.so.0) could not be loaded.

[root@aixsbx1][/] oslevel -s
7300-00-02-2220
[root@aixsbx1][/]

Hi Ken
Please remove openssl rpm package.

Thank you for that info.  
That was the fix