Ganesh,
There could be serveral reasons for this issue
First did you checked broker status? what did it say
In case broker is failed,it the issue with broker.Now you can check broker logs for failure
In case broker is running up and good,then synchronization is not happened.now it issue with IS
if broker is good,check for messaging settings in IS Admin.it shoud say “CONNECTED” and try to debug from MWS also to find more information
Thanks
Sai
#Universal-Messaging-Broker#webMethods#Integration-Server-and-ESB