You can find most of the details in readme file of the product. It provides details about deprecated services and compatibilities. Under the product documentation, you can also find fixes and enhacements document,which gives you details of fixes.
Coming to adapters and e-standards, check, what is the latest release and if you know, what versions of the adapters and e-standards your company wants to go with in IS 6.5. After figuring out the versions, the readme file of the version, will give you all the details required.
#Integration-Server-and-ESB#webMethods#Adapters-and-E-Standards