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This document provides best practices for using IBM Spectrum LSF with Nvidia DGX Systems. The document has been updated to cover NVIDIA DGX A100, including support for NVIDIA Multi-instance GPU (MIG) in Spectrum LSF for NVIDIA Ampere-based GPUs. The information contained in the document also applies to running IBM Spectrum LSF on accelerated IBM Power Systems servers, and x86 servers with Nvidia GPUs. #LSF#SpectrumComputingGroup#Spectrum-LSF