Reviewing the notes from the Known Issues section, I see the following

Known Issues - IBM Documentation 

I'm curious if anyone has more info on the scope or context (just maps, or other integration components?) and if there is a future roadmap decision to support ITX in the future.

Hi Matt, B2Bi 6.2.1 now uses Java 17 instead of Java 8. The issue is likely that you need a Java 17 version of ITX/ITXA if running integrated with B2Bi (as opposed to loosely coupled via REST for example). My understanding is that it is definitely in the plan to provide on-going support of ITX/ITXA with B2Bi. I'll forward this to product management and ask them to provide you with more detail.

Best regards.

@Matt Dorsey Hi Matt, ++ 

For information on future releases and product roadmap updates, including potential ITX/ITXA support, please subscribe to notifications here: https://www.ibm.com/support/pages/node/718119

Best regards.

Ashish Garg 

Thanks Ahish. According to ITX product management ITX 11.0.2 is scheduled for release soon so watch those notifications. This release is being tested with B2B Integrator 6.2.1 and ITXA 10.0.2.