Try the below if this helps:
1> Quit Designer if already open
2> Open command prompt and go to C:\SoftwareAG10\Designer\eclipse and run the command eclipse.exe -clean
3> Wait till the Designer pops up and try to connect
4> Still same issue, go to Window → Preferences ->Software AG → Integration Server. Select the Default name and click Edit. Make sure only “Connect immediately” is checked
5> Enter Host, Port, User and Password and click on Verify Server to see if you are able to connect to IS from Designer.
#webMethods-General#Integration-Server-and-ESB#webMethods