The new GENOSTAT (Genomic Analysis) procedure seems not to work on huge .fastq files (bigger than 3 GB): the data processing is not finishing even if frequencies analysis is requested for a single variable, resulting with a generic error message in the output, without any specific cause of the error.

For comparison, the files of the original demonstration at the IBM SPSS Statistics 32 site are successfully processed, but they are substantially smaller (less than 30 MB):

Are there any big .fastq files for which GENOSTAT properly works?

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Estefano Souza
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Hi @Estefano Souza, sorry you experienced difficulty with large .fastq files. Most likely your system ran out of memory while trying to process the large file. We are currently working on a solution whereby very large files will be broken down into smaller pieces so that machines with insufficient memory can still process these large files. We hope to have that solution ready by the 32.0.1 release in September.

Best regards,

Curtis

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---------------------------------------
Curtis Browning
IBM SPSS Statistics Architect
brownicu@us.ibm.com
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Thank you for the answer, @Curtis Browning.

One last question: is there any minimum hardware specifications for Genomic Analysis in SPSS Statistics (used during the IBM internal tests, for example)?

------------------------------
Estefano Souza
------------------------------

Original Message:
Sent: Mon May 25, 2026 12:18 PM
From: Curtis Browning
Subject: Genomic Analysis in SPSS Statistics 32: does it work?

Hi @Estefano Souza, sorry you experienced difficulty with large .fastq files. Most likely your system ran out of memory while trying to process the large file. We are currently working on a solution whereby very large files will be broken down into smaller pieces so that machines with insufficient memory can still process these large files. We hope to have that solution ready by the 32.0.1 release in September.

Best regards,

Curtis

------------------------------
---------------------------------------
Curtis Browning
IBM SPSS Statistics Architect
brownicu@us.ibm.com
---------------------------------------
------------------------------

Hi @Estefano Souza, there is no minimum system specification for using GENOSTAT. However, as with any program that attempts to process very large data, the more memory on one's system, the better.

Best,

Curtis

------------------------------
---------------------------------------
Curtis Browning
IBM SPSS Statistics Architect
brownicu@us.ibm.com
---------------------------------------
------------------------------

Original Message:
Sent: Mon May 25, 2026 03:44 PM
From: Estefano Souza
Subject: Genomic Analysis in SPSS Statistics 32: does it work?

Thank you for the answer, @Curtis Browning.

One last question: is there any minimum hardware specifications for Genomic Analysis in SPSS Statistics (used during the IBM internal tests, for example)?

------------------------------
Estefano Souza
------------------------------


Original Message:
Sent: Mon May 25, 2026 12:18 PM
From: Curtis Browning
Subject: Genomic Analysis in SPSS Statistics 32: does it work?

Hi @Estefano Souza, sorry you experienced difficulty with large .fastq files. Most likely your system ran out of memory while trying to process the large file. We are currently working on a solution whereby very large files will be broken down into smaller pieces so that machines with insufficient memory can still process these large files. We hope to have that solution ready by the 32.0.1 release in September.

Best regards,

Curtis

------------------------------
---------------------------------------
Curtis Browning
IBM SPSS Statistics Architect
brownicu@us.ibm.com